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Article

Transforming growth factor-12 polymorphism and systemic lupus erythematosus.

The Journal of rheumatology - 1 Jun 2002

Alansari Aliya, Hajeer Ali, Teh Lee-Suan, Bayat Ardeshir, Mysercough Anne, Gül Ahmet, Inanc Murat, Ordi-Ros Jose, Ollier William

Abstract excerpt

OBJECTIVE: To determine whether transforming growth factor-beta2 (TGF-beta2) gene polymorphism is associated with systemic lupus erythematosus (SLE) susceptibility. TGF-beta is a multifunctional family of cytokines important in tissue repair, inflammation and immunoregulation. SLE is thought to be a T cell dependent autoimmune disorder with T cell dysfunction. Due to its known suppressive effects on interleukin 2...

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PMID: 12064833

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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