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Article

A TNFR2 3' flanking region polymorphism in systemic lupus erythematosus.

Genes and immunity - 1 Feb 2000

Sullivan K E, Piliero L M, Goldman D, Petri M A

Abstract excerpt

The role of pro-inflammatory cytokines in systemic lupus erythematosus (SLE) remains somewhat controversial. Several studies have shown increased production of TNF alpha and IL-6 in patients with SLE. Increased production of IL-6, TNF alpha, and IL-1 soluble receptors have also been reported. This finding is provocative because the soluble receptors have the capacity to act as antagonists. Several other...

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Source

Identifiers

PMID: 11196716
DOI: 10.1038/sj.gene.6363662

Genes

TNF

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