Article
Mitochondrial DNA mutations in the parotid gland of cigarette smokers and non-smokers.
Mutation research - 27 Jun 2002
Lewis P D, Fradley S R, Griffiths A P, Baxter P W, Parry J M
Abstract excerpt
It has previously been demonstrated that mitochondrial DNA (mtDNA) mutations accumulate in the lung and increase in frequency with age. It has also been shown that the level of mtDNA mutations including deletions and base substitutions are elevated in lung tissue of smokers relative to non-smokers. We have previously shown that the 'common' 4977 bp mtDNA deletion is present in the parotid (salivary) gland of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.