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Decreased Mitochondrial DNA Content in Posttreatment Salivary Rinses from Head and Neck Cancer Patients

1 Mar 2006

Abstract excerpt

PURPOSE AND EXPERIMENTAL DESIGN: Alterations in mitochondrial DNA (mtDNA) sequence and content have been described in human tissues and tumors in association with smoking exposure. We did quantitative PCR analysis of cytochrome c oxidase (Cox) I and Cox II genes to measure changes in mtDNA content in pretreatment and posttreatment salivary rinses obtained from 76 patients undergoing surgical resection for primary...

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Share to Head and Neck Cancer Studies
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PMID: 16533782
DOI: 10.1158/1078-0432.ccr-05-1471

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