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Article

Genetic polymorphisms in UDP-glucuronosyltransferase 1A6 and 1A7 and the risk for benign Warthin's tumors of the parotid gland.

Head & neck - 1 Apr 2016

Lacko Martin, Voogd Adri C, van de Goor Rens C E, Roelofs Hennie M J, Te Morsche Rene H M, Bouvy Nicole D, Peters Wilbert H M, Manni Johannes J

Abstract excerpt

BACKGROUND: Warthin's tumors of the parotid gland are associated with smoking, whereas pleomorphic adenomas are not. Genetic polymorphisms in biotransformation enzymes, involved in detoxification of toxins and carcinogens in cigarette smoke, might modify the corresponding enzyme activity and influence detoxifying capacity. We hypothesize that these genetic polymorphisms may influence the individual risk for...

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PMID: 25899702
DOI: 10.1002/hed.24077

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