Article
Allelic imbalance in hMLH1 or BRCA2 loci associated with response of cervical and endometrial cancer to radiotherapy.
International journal of molecular medicine - 1 Jul 2002
Arvanitis Demetrios A, Angelakis Emmanouel, Koumantakis Eugenios E, Spandidos Demetrios A
Abstract excerpt
Effectiveness of radiotherapy is influenced by several genetic properties of the targeted cells. The aim of this study was the identification of prognostic indicators of tumor response to radiation in cervical and endometrial cancer. Using microsatellite DNA analysis, we investigated 31 markers, located on 1p, 2p, 2q, 3p, 9p, 9q, 13q, 17p and 17q for genomic alterations in 37 cervical and 21 endometrial cancer...
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