Article
Aneuploidy predicts outcome in patients with endometrial carcinoma and is related to lack of CDH13 hypermethylation.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2008
Suehiro Yutaka, Okada Toshiyuki, Okada Takae, Anno Keiko, Okayama Naoko, Ueno Koji, Hiura Mikako, Nakamura Mikiko, Kondo Tomoko, Oga Atsunori, Kawauchi Shigeto, Hirabayashi Kei, Numa Fumitaka, Ito Takehisa, Saito Toshiaki, Sasaki Kohsuke, Hinoda Yuji
Abstract excerpt
PURPOSE: Many investigators have reported that aneuploidy detected by flow cytometry is a useful prognostic marker in patients with endometrial cancer. Laser scanning cytometry (LSC) is a technology similar to flow cytometry but is more feasible for clinical laboratory use. We evaluated the usefulness of DNA ploidy detected by LSC as a prognostic marker in patients with endometrial cancer and investigated genetic...
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