Article
Evaluation of DNA mismatch repair system in cervical dysplasias and invasive carcinomas related to HPV infection.
European journal of gynaecological oncology - 1 Jan 2002
Kwaśniewska A, Goździcka-Józefiak A, Postawski K, Miturski R
Abstract excerpt
UNLABELLED: The aim of this study was to answer the question whether the products of hMSH2 and hMLH1 genes take part in the mutation track of cervical carcinoma. METHODS: IgG1 monoclonal antibodies (Pharmingen) detecting epitopes characteristic of hMLH1 and hMSH2 were used in the present study. The value of the half-quantitative H-score coefficient was calculated. Its threshold value was 0.4. Identification of 16...
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