Article
Genetic variants of the hemostatic system and development of transplant coronary artery disease.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Jun 2002
He Jian-Qing, Gaur Lakshmi K, Stempien-Otero April, Nelson Karen, Levy Wayne C, O'Brien Kevin D, Bolgiano Douglas C, Reiner Alexander P
Abstract excerpt
BACKGROUND: The occurrence of coronary artery disease (CAD) after heart transplantation may represent an accelerated inflammatory and thrombotic response to coronary vascular endothelial cell injury. Several common mutations involving hemostasis and cellular adhesion proteins have been associated with genetic susceptibility to native coronary heart disease. The clinical setting of heart transplantation provides a...
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