Article
ACE-gene polymorphism is associated with the development of allograft vascular disease in heart transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Dec 2000
Pethig K, Heublein B, Hoffmann A, Borlak J, Wahlers T, Haverich A
Abstract excerpt
BACKGROUND: Cardiac allograft vascular disease is (CAVD) the most important cause of death following heart transplantation (HTX). Although in the past, researchers focused predominantly on mechanisms of endothelial injury, the possible role of recipient-related and genetically determined factors has not been studied in detail. METHODS: Stimulated by recent observations in native coronary artery disease, we...
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