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Article

Human cardiosphere-seeded gelatin and collagen scaffolds as cardiogenic engineered bioconstructs.

Biomaterials - 1 Dec 2011

Chimenti Isotta, Rizzitelli Giuseppe, Gaetani Roberto, Angelini Francesco, Ionta Vittoria, Forte Elvira, Frati Giacomo, Schussler Olivier, Barbetta Andrea, Messina Elisa, Dentini Mariella, Giacomello Alessandro

Abstract excerpt

Cardiac tissue engineering (CTE) aims at regenerating damaged myocardium by combining cells to a biocompatible and/or bioactive matrix. Collagen and gelatin are among the most suitable materials used today for CTE approaches. In this study we compared the structural and biological features of collagen (C-RGD) or gelatin (G-FOAM)-based bioconstructs, seeded with human adult cardiac progenitor cells in the form of...

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Identifiers

PMID: 21890193
DOI: 10.1016/j.biomaterials.2011.08.049

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