Article
Characterization of structural and signaling molecules by human valve interstitial cells and comparison to human mesenchymal stem cells.
The Journal of heart valve disease - 1 Jan 2007
Latif Najma, Sarathchandra Padmini, Thomas Penny S, Antoniw Joe, Batten Puspa, Chester Adrian H, Taylor Patricia M, Yacoub Magdi H
Abstract excerpt
BACKGROUND AND AIM OF THE STUDY: Human mesenchymal stem cells (MSCs) are a potential cell source for the tissue engineering of biological structures, including cardiac valves. A comprehensive, phenotypic analysis of MSCs and, for the latter, their comparison with valve interstitial cells (ICs) is therefore essential. METHODS: Isolates of bone marrow-derived human MSCs and human cardiac valve ICs were extensively...
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