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Article

The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting.

Nature cell biology - 1 Jul 2002

Bilodeau Patricia S, Urbanowski Jennifer L, Winistorfer Stanley C, Piper Robert C

Abstract excerpt

Membrane proteins that are degraded in the vacuole of Saccharomyces cerevisiae are sorted into discrete intralumenal vesicles, analogous to the internal membranes of multi-vesiculated bodies (MVBs). Recently, it has shown that the attachment of ubiquitin (Ub) mediates sorting into lumenal membranes. We describe a complex of Vps27p and Hse1p that localizes to endosomal compartments and is required for the...

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Identifiers

PMID: 12055639
DOI: 10.1038/ncb815

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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