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Article

The yeast vps class E mutants: the beginning of the molecular genetic analysis of multivesicular body biogenesis.

Molecular biology of the cell - 1 Dec 2010

Coonrod Emily M, Stevens Tom H

Abstract excerpt

In 1992, Raymond et al. published a compilation of the 41 yeast vacuolar protein sorting (vps) mutant groups and described a large class of mutants (class E vps mutants) that accumulated an exaggerated prevacuolar endosome-like compartment. Further analysis revealed that this "class E compartment" contained soluble vacuolar hydrolases, vacuolar membrane proteins, and Golgi membrane proteins unable to recycle back...

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Identifiers

PMID: 21115849
DOI: 10.1091/mbc.E09-07-0603
PMCID: PMC2993735

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Source receipt: pubmed, retrieved 7 Sept 2026.

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