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Article

Production of transmitochondrial mice.

Methods (San Diego, Calif.) - 1 Apr 2002

Pinkert Carl A, Trounce Ian A

Abstract excerpt

With the advancement of various gene transfer technologies, the establishment of mitochondria transfer as a viable technique to genetically engineer mouse models paradoxically lagged behind other genetic technologies. The lack of demonstrable recombination in mtDNA necessitates different approaches to conventional transgenesis-based techniques. Initially, heteroplasmic mice were created to explore disease...

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Share to DNA
Share to DNA, Mitochondrial
Share to Genetic Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Mice, Transgenic

Share to Mitochondria

Share to Stem Cell Transplantation

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Identifiers

PMID: 12054926
DOI: 10.1016/S1046-2023(02)00041-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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