Attempts to understand the mechanisms of mitochondrial diseases: The reverse genetics of mouse models for mitochondrial disease.

Abstract excerpt

BACKGROUND: Mitochondrial disease is a general term for a disease caused by a decline in mitochondrial function. The pathology of this disease is extremely diverse and complex, and the mechanism of its pathogenesis is still unknown. Using mouse models that develop the disease via the same processes as in humans is the easiest path to understanding the underlying mechanism. However, creating a mouse model is...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cloning, Organism
• Share to Genome, Mitochondrial