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Article

Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP).

The Journal of biological chemistry - 9 Aug 2002

You Min, Fischer Monika, Deeg Mark A, Crabb David W

Abstract excerpt

Alcoholic fatty liver is the earliest and most common response of the liver to alcohol and may be a precursor of more severe forms of liver injury. The mechanism by which ethanol causes fatty liver and liver injury is complex. We found that in both rat H4IIEC3 and McA-RH7777 hepatoma cell lines, ethanol induced transcription of a sterol regulatory element-binding protein (SREBP)-regulated promoter via increased...

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Source

Identifiers

PMID: 12036955
DOI: 10.1074/jbc.M202411200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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