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Article

Development of an in vitro model to study hepatitis C virus effects on hepatocellular lipotoxicity and lipid metabolism.

Pathology, research and practice - 1 Oct 2018

Koletzko Leandra, Mahli Abdo, Hellerbrand Claus

Abstract excerpt

Hepatic steatosis is common in patients infected with hepatitis C virus (HCV). Particularly in patients infected with non-genotype 3 HCV, hepatic steatosis is closely related to factors of the metabolic syndrome such as hyperlipidemia. However, the molecular mechanisms involved in this "metabolic" steatosis in non-3 genotype HCV infections are not well understood. Here, we aimed to develop an in vitro model to...

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Identifiers

PMID: 30201523
DOI: 10.1016/j.prp.2018.08.013

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