Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Luminal Leptin Enhances CD147/MCT-1-mediated Uptake of Butyrate in the Human Intestinal Cell Line Caco2-BBE

1 Aug 2002

Abstract excerpt

In the intestine, butyrate constitutes the major energy fuel for colonocytes. However, little is known about the transport of butyrate and its regulation in the intestine. In this study we demonstrate that the monocarboxylate transporter (MCT-1) is apically polarized in model human intestinal epithelia and is involved in butyrate uptake by Caco2-BBE cell monolayers. The butyrate uptake by Caco2-BBE cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Treatment and Management
Share to Pancreatic function and diabetes
Share to Regulation of Appetite and Obesity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12034734
DOI: 10.1074/jbc.m203281200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Luminal Leptin Enhances CD147/MCT-1-mediated Uptake of Butyrate in the Human Intestinal Cell Line Caco2-BBEPMID 12034734Read ↗

The importance of colonic butyrate transport to the regulation of genes associated with colonic tissue homoeostasisSemantic proximity Read ↗

Butyrate combined with niacin promotes colonic metabolism and antimicrobial peptide expression to alleviate ETEC-induced colonic barrier dysfunction in weaned pigletsSemantic proximity Read ↗

Regulation of human colonic cell line proliferation and phenotype by sodium butyrate.Semantic proximity Read ↗

Divergent phenotypic patterns and commitment to apoptosis of Caco-2 cells during spontaneous and butyrate-induced differentiation.Semantic proximity Read ↗

Sodium butyrate alleviates deoxynivalenol-induced porcine intestinal barrier disruption by promoting mitochondrial homeostasis via PCK2 signalingSemantic proximity Read ↗

4-phenylbutyrate enhances the cell surface expression and the transport capacity of wild-type and mutated bile salt export pumps.Semantic proximity Read ↗

CD98-mediated links between amino acid transport and beta 1 integrin distribution in polarized columnar epithelia.Semantic proximity Read ↗

Imaging niacin trafficking with positron emission tomography reveals in vivo monocarboxylate transporter distributionSemantic proximity Read ↗

Analysis of the binding moiety mediating the interaction between monocarboxylate transporters and carbonic anhydrase II.Semantic proximity Read ↗

Physiological modulation of CFTR activity by AMP-activated protein kinase in polarized T84 cells.Semantic proximity Read ↗

Contrasting effects of butyrate on the expression of phenotypic markers of differentiation in neoplastic and non-neoplastic colonic epithelial cells in vitro.Semantic proximity Read ↗

Molecular mechanism of the intestinal biotin transport process.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.