Article

Butyrate combined with niacin promotes colonic metabolism and antimicrobial peptide expression to alleviate ETEC-induced colonic barrier dysfunction in weaned piglets

2025-11-25

Abstract excerpt

<title>Abstract</title> Background Butyrate is the primary energy substrate in the colon, whereas niacin can enhance energy metabolic flux by increasing nicotinamide adenine dinucleotide (NAD) synthesis. Therefore, this study aimed to investigate the effects of combining butyrate with niacin on colonic metabolism and resistance to enterotoxigenic <italic>Escherichia coli</italic> (ETEC) infection in weaned...

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Literature Corpus work: 2dca7da9-5423-5f68-be99-7337aa51481f
DOI: 10.21203/rs.3.rs-8061761/v1

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