Article
APOE gene polymorphisms and response to statin therapy.
The pharmacogenomics journal - 1 Aug 2009
Zintzaras E, Kitsios G D, Triposkiadis F, Lau J, Raman G
Abstract excerpt
Published studies investigating the role of APOE gene on lipid response (total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides) to statin treatment have reported inconsistent results. A meta-analysis was conducted to estimate the lipid response to statin treatment among APOE genetic variants (e2 carriers, e3e3 homozygotes and e4...
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