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Article

The influence of 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene promoter on the incidence, growth and operative risk of abdominal aortic aneurysm.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery - 1 May 2002

Jones K, Powell J, Brown L, Greenhalgh R, Jormsjö S, Eriksson P

Abstract excerpt

BACKGROUND: a single base pair deletion/insertion (4G/5G) polymorphism in the plasminogen activator inhibitor (PAI-1) promoter appears to influence PAI-1 synthesis (increased PAI-1 and inhibition of fibrinolysis with the 4G allele) and survival after severe trauma. OBJECTIVE: to identify whether the 4G/5G polymorphism influences the natural history of abdominal aortic aneurysm (AAA). METHODS: Four hundred and...

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Identifiers

PMID: 12027469
DOI: 10.1053/ejvs.2002.1633

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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