Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic analysis of oral tolerance to alloantigens: evidence that the indirect pathway of antigen presentation is involved.

Transplantation - 15 May 2002

Niederkorn Jerry Y, Mayhew Elizabeth

Abstract excerpt

BACKGROUND: Oral administration of alloantigens induces down-regulation of Th1 immune responses and reduces the incidence of corneal graft rejection. This study examined the role of Th1 and Th2 cytokines, accessory cells, and lymphoid organs that are known to be instrumental in other forms of antigen-specific tolerance. METHODS: Allogeneic dendritic cells (DC) were administered orally using a protocol that is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Administration, Oral
Share to Corneal Transplantation
Share to Fixatives

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Formaldehyde

Share to Isoantigens

Share to Receptors, Antigen, T-Cell, gamma-delta

Share to Thymus Gland

Share to Transplantation Tolerance

Source

Identifiers

PMID: 12023630
DOI: 10.1097/00007890-200205150-00021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic analysis of oral tolerance to alloantigens: evidence that the indirect pathway of antigen presentation is involved.PMID 12023630Read ↗

Oral Tolerance: Immunologic Mechanisms and Treatment of Animal and Human Organ-Specific Autoimmune Diseases by Oral Administration of AutoantigensSemantic proximity Read ↗

Dendritic cell modification as a route to inhibiting corneal graft rejection by the indirect pathway of allorecognition.Semantic proximity Read ↗

Innate profiles of cytokines implicated on oral tolerance correlate with low- or high-suppression of humoral response.Semantic proximity Read ↗

CD8+ EFFECTOR CELLS RESPONDING TO RESIDUAL CLASS I ANTIGENS, WITH HELP FROM CD4+ CELLS STIMULATED INDIRECTLY, CAUSE REJECTION OF ???MAJOR HISTOCOMPATIBILITY COMPLEX-DEFICIENT??? SKIN GRAFTS1Semantic proximity Read ↗

Treatment of donor corneal tissue with immunomodulatory cytokines: a novel strategy to promote graft survival in high-risk corneal transplantation.Semantic proximity Read ↗

Direct thymic involvement in anterior chamber-associated immune deviation: evidence for a nondeletional mechanism of centrally induced tolerance to extrathymic antigens in adult mice.Semantic proximity Read ↗

Tolerogenic dendritic cells suppress murine corneal allograft rejection by modulating CD28/CTLA-4 expression on regulatory T cells.Semantic proximity Read ↗

Donor-strain-derived immature dendritic cell pre-treatment induced hyporesponsiveness against allogeneic antigens.Semantic proximity Read ↗

Acquired immunostimulatory phenotype of migratory CD103+ DCs promotes alloimmunity following corneal transplantation.Semantic proximity Read ↗

Immunoregulatory functions for murine intraepithelial lymphocytes: gamma/delta T cell receptor-positive (TCR+) T cells abrogate oral tolerance, while alpha/beta TCR+ T cells provide B cell help.Semantic proximity Read ↗

Abortive alloantigen presentation by donor dendritic cells leads to donor-specific tolerance: a study with a preoperative CTLA4lg inoculation.Semantic proximity Read ↗

Oral tolerance in experimental autoimmune encephalomyelitis: specificity of peptide-induced oral tolerance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.