Regulation of sigma factor competition by the alarmone ppGpp.

Abstract excerpt

Many regulons controlled by alternative sigma factors, including sigma(S) and sigma(32), are poorly induced in cells lacking the alarmone ppGpp. We show that ppGpp is not absolutely required for the activity of sigma(S)-dependent promoters because underproduction of sigma(70), specific mutations in rpoD (rpoD40 and rpoD35), or overproduction of Rsd (anti-sigma(70)) restored expression from sigma(S)-dependent...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gene Expression Regulation, Bacterial
• Share to beta-Galactosidase
• Share to Binding, Competitive