Article
Rsd family proteins make simultaneous interactions with regions 2 and 4 of the primary sigma factor.
Molecular microbiology - 1 Dec 2008
Yuan Andy H, Gregory Brian D, Sharp Josh S, McCleary Katherine D, Dove Simon L, Hochschild Ann
Abstract excerpt
Bacterial anti-sigma factors typically regulate sigma factor function by restricting the access of their cognate sigma factors to the RNA polymerase (RNAP) core enzyme. The Escherichia coli Rsd protein forms a complex with the primary sigma factor, sigma(70), inhibits sigma(70)-dependent transcri...
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