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Article

The mutational specificity of the Dbh lesion bypass polymerase and its implications.

The Journal of biological chemistry - 2 Aug 2002

Potapova Olga, Grindley Nigel D F, Joyce Catherine M

Abstract excerpt

The Dbh polymerase of Sulfolobus solfataricus is a member of the recently described family of low fidelity DNA polymerases involved in bypass of DNA lesions. To investigate the enzymatic properties of Dbh, we characterized the errors made by this polymerase in vitro. Not only is Dbh much less accurate than the "classical" polymerases, but it showed a remarkable tendency to skip over a template pyrimidine...

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Identifiers

PMID: 12023283
DOI: 10.1074/jbc.M202607200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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