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Association analysis of the 5-HT6 receptor polymorphism C267T with depression in patients with Alzheimer's disease.

Psychiatry and clinical neurosciences - 1 Aug 2001

Liu H C, Hong C J, Liu C Y, Lin K N, Tsai S J, Liu T Y, Chi C W, Wang P N

Abstract excerpt

A significant increase of 267C allele of the 5-HT(6) receptor gene has been reported in patients with Alzheimer's disease (AD). Because a deficit in serotonergic neurotransmission is involved in major depression, we tried to find out whether 267C allele is associated with depressive disorders in AD. A psychiatrist interviewed all AD patients and their caregivers for evidence of depression using a Chinese version...

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Identifiers

PMID: 11442897
DOI: 10.1046/j.1440-1819.2001.00886.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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