Article
Effects of malonate C60 derivatives on activated microglia.
Brain research - 14 Jun 2002
Tzeng Shun-Fen, Lee Jia-Ling, Kuo Jon-Sun, Yang Chung-Shi, Murugan Periyagamy, Ai Tai Lin, Chu Hwang Kuo
Abstract excerpt
Activated microglia in acute and chronic neurodegenerative disease of the central nervous system (CNS) can produce large amounts of free radicals, such as reactive oxygen species (ROS), which subsequently contribute to neuropathogenesis. Thus, it is believed that the induction of microglial deactivation can reduce neuronal injury. Buckminsterfullerene (C60) derivatives that possess free radical scavenging...
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