Article
Contribution of the interleukin 4 gene to susceptibility to subacute sclerosing panencephalitis.
Archives of neurology - 1 May 2002
Inoue Takehiko, Kira Ryutaro, Nakao Futoshi, Ihara Kenji, Bassuny Wafaa M, Kusuhara Koichi, Nihei Kenji, Takeshita Kenzo, Hara Toshiro
Abstract excerpt
BACKGROUND: Although the exact pathogenesis of subacute sclerosing panencephalitis (SSPE) remains to be determined, both viral and host factors seem to be involved. OBJECTIVE: To identify host genetic factors involved in the development of SSPE. METHODS: We investigated the association of polymorphisms in the T helper (Th)1 and Th2 cytokine, and related genes (interferon [IFN]-gamma, IFN-gamma receptor 1...
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