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Article

Exploring the role of the IL-12/IFN-γ immune axis in subacute sclerosing panencephalitis.

Journal of neuroimmunology - 15 Mar 2025

Viswanathan L G, Babu Gopika Suresh, Dey Saikat, Kavya Paranthaman V, Mullapudi Thrinath, Thennarasu Kandavel, Ravindranadh Mundlamuri, Kenchaiah Raghavendra, Nagappa Madhu, Seshagiri Doniparthi, Asranna Ajay, Sinha Sanjib, Debnath Monojit

Abstract excerpt

BACKGROUND: Subacute sclerosing panencephalitis (SSPE) is a rare but fatal neurological syndrome resulting from persistent measles virus infection in the central nervous system. Despite the availability of a measles vaccine, SSPE continues to pose a significant health burden, and immunogenetic risk factors remain unclear. We aimed to study the role of the interleukin 12 (IL-12)/interferon-gamma (IFN-γ) axis,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39955927
DOI: 10.1016/j.jneuroim.2025.578532

Genes

IFNGR1
IFNGR2
ISG15
IFNG
STAT4
STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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