Article
IL28B, IL29 and micro-RNA 548 in subacute sclerosing panencephalitis as a rare disease.
Gene - 15 Dec 2018
Cakmak Genc Gunes, Dursun Ahmet, Karakas Celik Sevim, Calik Mustafa, Kokturk Furuzan, Piskin Ibrahim Etem
Abstract excerpt
Subacute sclerosing panencephalitis (SSPE) is a progressive neurodegenerative disease which affects children and young adults, caused by a persistent infection of defective measles virus. IFN-λs (IL-28A, IL-28B and IL-29) are a group of cytokines mediating antiviral responses. It has been shown that IL-29 levels are significantly higher in infected cells with defective measles virus. IL-29 expression is thought...
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