Article
Analysis of MxA, IL-4, and IRF-1 genes in Filipino patients with subacute sclerosing panencephalitis.
Neuropediatrics - 1 Aug 2006
Pipo-Deveza J R, Kusuhara K, Silao C L T, Lukban M B, Salonga A M, Sanchez B C, Kira R, Takemoto M, Torisu H, Hara T
Abstract excerpt
BACKGROUND: Subacute sclerosing panencephalitis (SSPE) is a chronic and debilitating disease of the central nervous system caused by a latent measles virus infection. Three candidate genes, MxA, IL-4, and IRF-1 genes were shown to be associated with SSPE in Japanese patients. These genes have been suggested to play a role in the establishment of persistent viral infection in the central nervous system. SUBJECTS...
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