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Article

Association of toll-like receptor 3 gene polymorphism with subacute sclerosing panencephalitis.

Journal of neurovirology - 1 Nov 2008

Ishizaki Yoshito, Takemoto Megumi, Kira Ryutaro, Kusuhara Koichi, Torisu Hiroyuki, Sakai Yasunari, Sanefuji Masafumi, Yukaya Naoko, Hara Toshiro

Abstract excerpt

Innate immunity plays an important role in measles virus (MV) infection. MV-derived double-stranded RNA is recognized by toll-like receptor 3 (TLR3), retinoic acid-inducible protein I (RIG-I) and melanoma differentiation-associated gene 5 (MDA5). We investigated whether genes encoding these molecules contributed to the development of subacute sclerosing panencephalitis (SSPE) in Japanese individuals. Four single...

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Source

Identifiers

PMID: 19016379
DOI: 10.1080/13550280802298120

Genes

TLR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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