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Article

Mechanism of selective recruitment of RNA polymerases II and III to snRNA gene promoters.

Genes & development - 1 May 2018

Dergai Oleksandr, Cousin Pascal, Gouge Jerome, Satia Karishma, Praz Viviane, Kuhlman Tracy, Lhôte Philippe, Vannini Alessandro, Hernandez Nouria

Abstract excerpt

RNA polymerase II (Pol II) small nuclear RNA (snRNA) promoters and type 3 Pol III promoters have highly similar structures; both contain an interchangeable enhancer and "proximal sequence element" (PSE), which recruits the SNAP complex (SNAPc). The main distinguishing feature is the presence, in the type 3 promoters only, of a TATA box, which determines Pol III specificity. To understand the mechanism by which...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29785964
DOI: 10.1101/gad.314245.118
PMCID: PMC6004067

Genes

TBP
BRF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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