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Transcription Factor AP-2γ Is a Developmentally Regulated Marker of Testicular Carcinoma<b><i>In situ</i></b>and Germ Cell Tumors

15 Dec 2004

Abstract excerpt

PURPOSE: Transcription factor activator protein-2gamma (TFAP2C, AP-2gamma) was reported previously in extraembryonic ectoderm and breast carcinomas but not in the testis. In our recent gene expression study we detected AP-2gamma in carcinoma in situ testis (CIS, or intratubular germ cell neoplasia), precursor of testicular germ cell tumors. In this study we aimed to investigate the expression pattern of AP-2gamma...

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PMID: 15623634
DOI: 10.1158/1078-0432.ccr-04-1285

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