Article
A novel mutation vf causing abnormal vacuoles in the central nervous system maps on rat chromosome 8.
Experimental animals - 1 Apr 2002
Nakane Yoshifumi, Adachi Tamiko, Voigt Birger, Yamasaki Ken-ichi, Kaji Sumiko, Inui Toshihide, Kitada Kazuhiro, Serikawa Tadao
Abstract excerpt
Body-tremorous rats were found in a colony of WTC-tm rats and a new coisogenic mutant strain void of the tm mutation was established. Histological analysis revealed that these rat mutants had abnormal vacuoles in the red nucleus of the midbrain, the reticular formation in the brain stem, and the white matter of the cerebellum and spinal cord. Electron microscopic observation showed many irregular myelin-bound...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
