Epileptic seizures in rats homozygous for two mutations, zitter and tremor.

Abstract excerpt

In the rat, zitter (zi) and tremor (tm) are autosomal recessive mutations that in homozygotes caused curled whisker hair, and tremor when the animals move. In both mutant types, the presence of many vacuoles gives the central nervous system a spongy appearance. The mutants differ sharply in one important characteristic: zitter rats are fertile, tremor rats are sterile. The F1 hybrids between zitter homozygous...

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