Article
Sleep-time variation for ethanol and the hypnotic drugs tribromoethanol, urethane, pentobarbital, and propofol within outbred ICR mice.
Experimental animals - 1 Apr 2002
Koizumi Tsutomu, Maeda Hideyuki, Hioki Kyoji
Abstract excerpt
To evaluate the phenotypic variation within a commercial outbred mouse stock, we examined sleep-time (or duration of loss of righting reflex) of outbred ICR mice after i.p. injection of ethanol (4.0 g/kg of body weight), urethane (1.3 g), tribromoethanol (250 mg), and pentobarbital (60 mg), and after i.v. injection of propofol (30 mg). We observed high-grade individual differences in sleep-time that ranged from 0...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.