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Article

Pharmacogenetic variability in neuronal nicotinic receptor-mediated antinociception.

Pharmacogenetics - 1 Oct 1999

Flores C M, Wilson S G, Mogil J S

Abstract excerpt

The ability to predict interindividual differences in drug efficacy or toxicity, based on genetic factors that influence drug disposition or drug action, is fast becoming a realistic goal. The purpose of the present study was to determine whether epibatidine, a prototypical nicotinic analgesic drug, exhibits pharmacogenetic variability in antinociceptive activity. Eight inbred mouse strains (A, AKR, BALB/c,...

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Source

Identifiers

PMID: 10591542

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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