Genetic variation in outbred rats and mice and its implications for toxicological screening.

Abstract excerpt

There are two basic types of laboratory rodent used in toxicological screening. Isogenic (inbred) strains are rather like clones of genetically identical individuals whereas outbred stocks are usually more variable, though the amount of variability depends on the previous history of the colony. I...

Topics

• Animals
• Breeding
• Drug Evaluation, Preclinical
• Genetic Variation
• Mice
• Phenotype
• Rats
• Toxicology