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Article

Overexpression of truncated gamma-tubulins disrupts mitotic aster formation in Xenopus oocyte extracts.

The Biochemical journal - 1 Aug 2005

Kotani Tomoya, Yamashita Masakane

Abstract excerpt

Mechanisms of spindle pole formation rely on minus-end-directed motor proteins. gamma-Tubulin is present at the centre of poles, but its function during pole formation is completely unknown. To address the role of gamma-tubulin in spindle pole formation, we overexpressed GFP (green fluorescent protein)-fused gamma-tubulin (gamma-Tu-GFP) in Xenopus oocytes and produced self-assembled mitotic asters in the oocyte...

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Identifiers

PMID: 15819612
DOI: 10.1042/BJ20050243
PMCID: PMC1180710

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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