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Article

Mutations in nonstructural protein 5A gene and response to interferon in hepatitis C virus genotype 2 infection.

Hepatology (Baltimore, Md.) - 1 Oct 1999

Murakami T, Enomoto N, Kurosaki M, Izumi N, Marumo F, Sato C

Abstract excerpt

An association has been reported between mutations in the amino acid residues 2209-2248 of the nonstructural protein 5A (NS5A) gene (interferon-sensitivity determining region [ISDR]) and interferon efficacy in hepatitis C virus (HCV)-1b infection. This relationship was analyzed in chronic HCV-2 infection. Forty patients with HCV-2a and 35 with HCV-2b were treated with interferon alfa for 6 months with a total...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10498658
DOI: 10.1002/hep.510300405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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