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Article

ADAM 12 protease induces adipogenesis in transgenic mice.

The American journal of pathology - 1 May 2002

Kawaguchi Nobuko, Xu Xiufeng, Tajima Rie, Kronqvist Pauliina, Sundberg Christina, Loechel Frosty, Albrechtsen Reidar, Wewer Ulla M

Abstract excerpt

ADAM 12 (meltrin-alpha) is a member of the ADAM (a disintegrin and metalloprotease) family. ADAM 12 functions as an active metalloprotease, supports cell adhesion, and has been implicated in myoblast differentiation and fusion. Human ADAM 12 exists in two forms: the prototype membrane-anchored protein, ADAM 12-L, and a shorter secreted form, ADAM 12-S. Here we report the occurrence of adipocytes in the skeletal...

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Share to ADAM Proteins
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Share to Adipose Tissue

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12000741
DOI: 10.1016/S0002-9440(10)61136-4
PMCID: PMC1850877

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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