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Article

Lessons on Conditional Gene Targeting in Mouse Adipose Tissue

16 Jan 2013

Abstract excerpt

Conditional gene targeting has been extensively used for in vivo analysis of gene function in adipocyte cell biology but often with debate over the tissue specificity and the efficacy of inactivation. To directly compare the specificity and efficacy of different Cre lines in mediating adipocyte specific recombination, transgenic Cre lines driven by the adipocyte protein 2 (aP2) and adiponectin (Adipoq) gene...

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Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
Share to Lipid metabolism and biosynthesis

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PMID: 23321074
DOI: 10.2337/db12-1089

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