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Article

Tumor necrosis factor alpha-gene therapy for an established murine melanoma using RGD (Arg-Gly-Asp) fiber-mutant adenovirus vectors.

Japanese journal of cancer research : Gann - 1 Apr 2002

Okada Yuka, Okada Naoki, Nakagawa Shinsaku, Mizuguchi Hiroyuki, Takahashi Koichi, Mizuno Nobuyasu, Fujita Takuya, Yamamoto Akira, Hayakawa Takao, Mayumi Tadanori

Abstract excerpt

Although adenovirus vectors (Ad) provide high-level transduction efficacy to many cell types, extremely high doses of Ad are required for sufficient gene transduction into several tumors, including melanoma. Here, we demonstrated that the expression of coxsackie-adenovirus receptor, a primitive Ad-receptor, was very low in murine and human melanoma cells. We also found that fiber-mutant Ad containing the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11985794
DOI: 10.1111/j.1349-7006.2002.tb01275.x
PMCID: PMC5927019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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