Article
A Bayesian partition model for case-control studies on highly polymorphic candidate genes.
Genetic epidemiology - 1 Apr 2002
Seaman S R, Richardson S, Stücker I, Benhamou S
Abstract excerpt
We present a new statistical model for the analysis of case-control or cohort studies examining a highly polymorphic candidate disease susceptibility gene. Many genotypes are possible for such a gene. Consequently, the average number of subjects having each genotype will be modest. If analyzed separately, the risks associated with most genotypes will be estimated imprecisely. Our Bayesian partition model clusters...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
