Article
Equivalence of three score tests for association mapping of quantitative trait loci under selective genotyping.
Genetic epidemiology - 1 Jul 2010
Tang Yongqiang
Abstract excerpt
Huang and Lin ([2007] Am J Hum Genet 80:567-572) proposed a conditional-likelihood approach for mapping quantitative trait loci (QTL) under selective genotyping, and demonstrated via simulation that their model tends to be more powerful than the prospective linear regression. However, we show that the three score tests based on the conditional, prospective and retrospective likelihoods are numerically identical...
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