Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of chromosome 22 and absence of NF2 gene mutation in a case of multiple meningiomas.

Human pathology - 1 Mar 2002

Lomas Jesus, Bello M Josefa, Alonso M Eva, Gonzalez-Gomez Pilar, Arjona Dolores, Kusak M Elena, de Campos Jose M, Sarasa Jose L, Rey Juan A

Abstract excerpt

Multiple meningiomas are rare, and only 13 cases have been subjected to molecular genetic analysis to detect mutations of the tumor-suppressor gene neurofibromatosis type 2 (NF2) located on chromosome 22. Most of these cases display NF2 gene mutations parallel to loss of the chromosome 22 homolog, indicating that inactivation of this gene may represent an early event in the development of multiple meningiomas. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Deletion
Share to Chromosomes, Human, Pair 22

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Neurofibromatosis 2

Share to Meningeal Neoplasms

Share to Meningioma

Share to Mutation

Source

Identifiers

PMID: 11979381
DOI: 10.1053/hupa.2002.32229

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of chromosome 22 and absence of NF2 gene mutation in a case of multiple meningiomas.PMID 11979381Read ↗

Familial meningioma is not allelic to neurofibromatosis 2.Semantic proximity Read ↗

Deletions on chromosome 22 in sporadic meningiomaSemantic proximity Read ↗

Deletion mapping of the long arm of chromosome 22 in human meningiomasSemantic proximity Read ↗

Predominant occurrence of somatic mutations of the NF2 gene in meningiomas and schwannomas.Semantic proximity Read ↗

Multiple meningiomas: Investigating the molecular basis of sporadic and familial formsSemantic proximity Read ↗

Interstitial loss and gain of sequences on chromosome 22 in meningiomas with normal karyotype.Semantic proximity Read ↗

Molecular Genetics of Neurofibromatosis 2 and Related Tumors (Acoustic Neuroma and Meningioma)<sup>a</sup>Semantic proximity Read ↗

Genetic and epigenetic alteration of the NF2 gene in sporadic meningiomas.Semantic proximity Read ↗

Comprehensive genetic and epigenetic analysis of sporadic meningioma for macro-mutations on 22q and micro-mutations within the NF2 locus.Semantic proximity Read ↗

Analysis of the neurofibromatosis 2 gene reveals molecular variants of meningioma.Semantic proximity Read ↗

Ring chromosome 22 and neurofibromatosis type II: proof of two-hit model for the loss of the NF2 gene in the development of meningioma.Semantic proximity Read ↗

Screening for mutations in the neurofibromatosis type 2 (NF2) gene in sporadic meningiomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.