Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic screen yields mutations in genes encoding all known components of the Escherichia coli signal recognition particle pathway.

Journal of bacteriology - 1 Jan 2002

Tian Hongping, Beckwith Jon

Abstract excerpt

We describe the further utilization of a genetic screen that identifies mutations defective in the assembly of proteins into the Escherichia coli cytoplasmic membrane. The screen yielded mutations in each of the known genes encoding components of the E. coli signal recognition particle pathway: ffh, ffs, and ftsY, which encode Ffh, 4.5S RNA, and FtsY, respectively. In addition, the screen yielded mutations in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Maltose-Binding Proteins
Share to Monosaccharide Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multidrug Resistance-Associated Proteins

Share to Periplasm

Share to Receptors, Cytoplasmic and Nuclear

Share to SEC Translocation Channels

Share to SecA Proteins

Share to Signal Recognition Particle

Source

Open in PubMed Open full text

Identifiers

PMID: 11741850
DOI: 10.1128/JB.184.1.111-118.2002
PMCID: PMC134764

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic screen yields mutations in genes encoding all known components of the Escherichia coli signal recognition particle pathway.PMID 11741850Read ↗

A mutant hunt for defects in membrane protein assembly yields mutations affecting the bacterial signal recognition particle and Sec machinery.Semantic proximity Read ↗

Functional analysis of the signal recognition particle in Escherichia coli by characterization of a temperature-sensitive ffh mutant.Semantic proximity Read ↗

Characterization of conserved bases in 4.5S RNA of Escherichia coli by construction of new F' factors.Semantic proximity Read ↗

Secretion defects that activate the phage shock response of Escherichia coli.Semantic proximity Read ↗

The signal recognition particle (SRP) RNA links conformational changes in the SRP to protein targeting.Semantic proximity Read ↗

Partial suppression of Oxa1 mutants by mitochondria-targeted signal recognition particle provides insights into the evolution of the cotranslational insertion systems.Semantic proximity Read ↗

An E. coli ribonucleoprotein containing 4.5S RNA resembles mammalian signal recognition particle.Semantic proximity Read ↗

Characterization of transmembrane domains 6, 7, and 8 of MalF by mutational analysis.Semantic proximity Read ↗

The functional integration of a polytopic membrane protein of Escherichia coli is dependent on the bacterial signal-recognition particle.Semantic proximity Read ↗

Substitution of fifty four homologue (Ffh) in Escherichia coli with the mammalian 54-kDa protein of signal-recognition particle.Semantic proximity Read ↗

asmB, a suppressor locus for assembly-defective OmpF mutants of Escherichia coli, is allelic to envA (lpxC).Semantic proximity Read ↗

Inefficient Tat-dependent export of periplasmic amidases in an Escherichia coli strain with mutations in two DedA family genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.