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Article

Fas, ceramide and serum withdrawal induce apoptosis via a common pathway in a type II Jurkat cell line.

Cell death and differentiation - 1 May 2002

Caricchio R, D'Adamio L, Cohen P L

Abstract excerpt

Ceramide is a key mediator of apoptosis, yet its role in Fas-mediated apoptosis is controversial. Some reports have indicated that ceramide is either a primary signaling molecule in Fas-induced cell death, or that it functions upstream of Fas by increasing FasL expression. Other studies have suggested that ceramide is not relevant to Fas-induced cell death. We have approached this problem by studying...

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PMID: 11973615
DOI: 10.1038/sj.cdd.4400996

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Fas, ceramide and serum withdrawal induce apoptosis via a common pathway in a type II Jurkat cell line.PMID 11973615Read ↗

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